Recently we have played around with the idea of doing a 100% Brettanomyces fermented beer. This definitely is not the first time it has been done, but this one will be our first. Usually beer is fermented either with a lager or ale yeast. If any wild cultures are added (either wild yeast or lactic bacteria,) most brewers have been adding them as a secondary fermentation.
We have taken a new bourbon barrel, added a light, hoppy wort, added a pitchable quantity of Brettanomyces bruxellensis and let it go. This beer should hopefully be around 5-6%. It could be a train wreck, it could be great, or anywhere in between. I guess that is why they call it an experiment. Yea craft brewing!